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OsrHSA, Recombinant Human Serum Albumin(Clinical Grade)

OsrHSA, Recombinant Human Serum Albumin(Clinical Grade) 

 

Source: Rice Grain (Oryza Sativa)

 

Catalog No:

HYC002C01 (Lyophilized powder)

HYC001C01 (Liquid, 20%)

 

DMF No.: #029648

 

Introduction:            

Human serum albumin is the most abundant protein in human plasma. It can transport hormones, lipids and other molecules and maintain osmotic pressure. OsrHSA is a recombinant human serum albumin derived from rice grains, which provides an excellent solution for animal free medium. Compared to FBS, pHSA and BSA, OsrHSA has higher purity and excellent batch consistency. Meanwhile, OsrHSA is widely used as excipient, stabilizer and embedding agent in bio-pharmaceutical applications.

 

Physical Appearance:

Off-white to light beige lyophilized powder (HYC002C01)

Slightly sticky, yellow or brown transparent liquid (HYC001C01)

 

Formulation:

It is lyophilized with saline (HYC002C01).

It is packaged in 50ml with 20% concentration (HYC001C01).

 

Purity: More than 99.99% as determined by SDS-PAGE and HPLC analysis.

 

Endotoxin: Less than 0.01EU/mg

 

Applications:

Mammalian cell culture

Vaccine manufacture and formulation

Bio-pharmaceutical production and formulation

Drug delivery

In vivo/vitro diagnostics

Cryopreservation of cell

Coating of medical devices

 

Storage and Handling:

Stored at temperatures 2-8 for 24 months (HYC002C01, HYC001C01). For lyophilized powder, it is recommended to reconstitute the lyophilized OsrHSA in sterile PBS. Upon reconstitution, OsrHSA should be stored below -20. Use as soon as possible after opening. Please avoid freeze-thaw cycles.

 

1. HPLC analysis          

OsrHSA was analyzed by size exclusion chromatography HPLC (SEC HPLC), showing the purity is more than 99.99%.

 

2. OsrHSA has equal safety in Vivo to pHSA

 

The titers of individual immunoglobulins IgG, IgM, IgE, and IgA showed no significant difference among the pHSA, OsrHSA, and saline groups, and the titers of C4 complement were not significantly different.

   

3. Performance of OsrHSA in CIK cell therapy


OsrHSA was used in PBMC culture to induce the CIK cells. After 14 days, the total cell amount reach to 6.6X109, and

the CD3+CD56+ rate is more than 22.97%. It showed that OsrHSA has effective action in promoting CIK cell growth.

 

 

Publication
  • Doxorubicin-Loaded Glycyrrhetinic Acid Modified Recombinant Human Serum Albumin Nanoparticles for Tar

  • Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem Cells

  • Transgenic rice endosperm as a bioreactor for molecular pharming

  • Quantitation ofthe residual DNA from rice-derived recombinant human serum albumin

  • Human serum albumin from recombinant DNA technology: Challenges and strategies

  • Wen-Wen Qi,et al.Doxorubicin-Loaded Glycyrrhetinic Acid Modified Recombinant Human Serum Albumin Nan

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