Human basic fibroblast growth factor, also known as bFGF, FGF2 or FGF-β, is a member of the fibroblast growth factor family. It is a single-chain polypeptide growth factor that plays a significant role in the process of promoting cell proliferation, inhibiting cell apoptosis, expediting wound healing and inducing angiogenesis. It is also a very potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages.
The ED50 is ≤1ng/ml determined by a cell proliferation assay using Balb/c 3T3, corresponding to a specific activity of ≥1×106 Units/mg.
Mammalian cell culture
Cosmetic and beauty care
Storage and Handling:
Stored at temperatures -20℃ for at least 24 months. It is recommended to reconstitute the lyophilized OsrbFGF in sterile water. Use as soon as possible after opening. Please avoid freeze-thaw cycles.
FOR RESEARCH, LABORATORY AND MANUFACTURE USE ONLY. NOT INTENDED FOR DIRECT USE ON HUMANS.
Compared OsrbFGF with rbFGF in MSC culture
Compared OsrbFGF with rbFGF in iPS cell culture
OsrbFGF sample showed almost equal performance for feeder-free culture of iPS cells compared to control rbFGF (E.coli) .